(1) 國(guó)家自然科學(xué)基金委員會(huì), 面上項(xiàng)目, 32070602, 利用CRISPR-Cas9技術(shù)構(gòu)建ASGR1基因敲除豬作為人類動(dòng)脈粥樣硬化疾病模型的研究, 2021-01-01 至 2024-12-31, 58萬元, 在研, 參與
(2) 國(guó)家自然科學(xué)基金委員會(huì), 面上項(xiàng)目, 31772863, 內(nèi)質(zhì)網(wǎng)應(yīng)激參與DHA促進(jìn)草魚脂肪細(xì)胞脂解過程的機(jī)制研究, 2018-01-01 至 2021-12-31, 61萬元, 結(jié)題, 參與
1. Xiao Chen Shi#, Bo Xia#, Jian Feng Zhang, Rui Xin Zhang, Dan Yang Zhang, Huan Liu, Bao Cai Xie, Yong Liang Wang*, and Jiang Wei Wu*. "Optineurin promotes myogenesis during muscle regeneration in mice by autophagic degradation of GSK3β." PLoS biology 20, no. 4 (2022): e3001619. (中科院一區(qū)，top期刊，Nature Index期刊，IF=9.593)
2. Bao Cai Xie#, Xiao chen Shi#, Yan Li#, Bo Xia, Jia Zhou, Min Jie Du, Xiang Yang Xing, Liang Bai, En Qi Liu, Fernando Alvarez, Long Jin, Shao Ping Deng, Grant A. Mitchell, Deng Ke Pan*, Ming Zhou Li*, Jiang Wei Wu*. "Deficiency of ASGR1 in pigs recapitulates reduced risk factor for cardiovascular disease in humans." PLoS genetics 17, no. 11 (2021): e1009891. (中科院二區(qū)，top期刊，Nature Index期刊，IF=6.020)
3. Xia Bo#, Xiao Chen Shi#, Bao Cai Xie#, Meng Qing Zhu, Yan Chen, Xin Yi Chu, Guo He Cai, Min Liu, Shi Zhen Yang, Grant A. Mitchell, Wei Jun Pang*, Jiang Wei Wu*. "Urolithin A exerts antiobesity effects through enhancing adipose tissue thermogenesis in mice." PLoS biology 18, no. 3 (2020): e3000688. (中科院一區(qū)，top期刊，Nature Index期刊，IF=9.593)
4. Xiao Chen Shi, Ai Jin, Jian Sun, Jing Jing Tian, Hong Ji*, Li Qiao Chen, Zhen Yu Du. "The protein-sparing effect of α-lipoic acid in juvenile grass carp, Ctenopharyngodon idellus: effects on lipolysis, fatty acid β-oxidation and protein synthesis." British Journal of Nutrition 120, no. 9 (2018): 977-987. (中科院三區(qū)，IF=4.125)
5. Xiao Chen Shi, Jian Sun, Ai Jin, Hong Ji*, Hai Bo Yu, Yang Li, Xue Xian Li, Pin Liu, Chao Li, Ji Qin Huang. "Cytochrome P450 2AA molecular clone, expression pattern, and different regulation by fish oil and lard oil in diets of grass carp (Ctenopharyngodon idella)." Fish physiology and biochemistry 44, no. 4 (2018): 1019-1026. (中科院三區(qū)，IF=3.014)
6. Xiao Chen Shi, Ai Jin, Jian Sun, Zhou Yang, Jing Jing Tian, Hong Ji*, Hai Bo Yu, Yang Li, Ji Shu Zhou, Zhen Yu Du, Li Qiao Chen. "α-lipoic acid ameliorates n-3 highly-unsaturated fatty acids induced lipid peroxidation via regulating antioxidant defenses in grass carp (Ctenopharyngodon idellus)." Fish & shellfish immunology 67 (2017): 359-367. (中科院二區(qū)，top期刊，IF=4.622)
7. Xiao Chen Shi, Jian Sun, Zhou Yang, Xue Xian Li, Hong Ji*, Yang Li, Zhi Guang Chang, Zhen Yu Du, Li Qiao Chen. "Molecular characterization and nutritional regulation of carnitine palmitoyltransferase (CPT) family in grass carp (Ctenopharyngodon idellus)." Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 203 (2017): 11-19. (中科院三區(qū)，IF=2.495)
8. Xiao Chen Shi，et al., " Optineurin (OPTN) interacts with JUP/PI3K complex in the PI3K/AKT/mTOR pathway to prevent muscle atrophy." PLoS biology (In preparation)
