
段金菊
女,57歲,漢族,中國共產黨黨員,c7c7.app第二醫院藥學部副主任,主任藥師,博士,博士生導師。
E-mail:duanjinju@163.com
教育經歷
2016.12.10-12.18 美國約翰霍普金斯大學藥學研修
2004.09-2007.07 c7c7.app 內科學博士
1999.09-2002.07 c7c7.app 藥理學碩士
1984.09-1988.07 天津第二醫學院 藥學學士
工作經歷
至今c7c7.app藥學院客座教授
2010.5-至今c7c7.app第二醫院主任藥師
2003.5-2010.4c7c7.app第二醫院副主任藥師
1998.5-2003.4c7c7.app第二醫院主管藥師
1988.5-1998.4c7c7.app第二醫院藥師
學術任職
《中國醫院藥學雜志》編委;《c7c7.app學報》編委;《中國臨床藥理學》青年編委; c7c7.app兼職教授; 山西省學術技術帶頭人; 山西省“三晉英才”拔尖骨干人材。
社會兼職:國家藥事管理專業質控中心專家委員會成員;中國醫院協會藥事管理專業委員會常務委員;中國藥學會抗生素專業委員會委員;全國抗真菌病監測網質量管理中心委員;全國抗菌藥物監測網及真菌病監測網山西分網負責人;全國老年藥學聯盟常務理事;山西省醫學會微生物與免疫學專業委員會主任委員;山西省藥師協會合理用藥分會主任委員;山西省衛生廳醫療質量控制中心藥事質控部副主任;山西省醫學會臨床藥學專業委員會副主任委員。
榮譽獲獎
先后承擔了省級科研課題6項,以主持人獲山西省科技進步二等獎、三等獎各一項。
教學情況
2006年起協助指導研究生12名,2010年起至今指導研究生共30名。
2019年至今講授臨床藥學本科課程--臨床藥理學。
研究領域
現主要從事細菌耐藥機制研究和藥物基因組學研究,先后承擔了省級科研課題6項。以第一作者和通訊作者發表論文70余篇,其中SCI 20多篇。
代表性科研、教改項目
1、同種異體骨軟骨移植生物安全保障體系的構建,中華人民共和國科學技術部國家重點研發計劃,2024,150萬元
2、有機合成分子MTEBT-3對碳青霉烯類耐藥的肺炎克雷伯菌(CRKP)抗耐藥、抗毒力和破膜機制的研究,山西省科技廳,2024,8萬元
3、建立三級基層藥學服務規范,保障基層慢病患者用藥安全,基層適宜性技術推廣項目,202305,5萬元
4、吳階平醫學基金,320.6750.2021-08-8,電荷可控納米脂質體藥物對抗銅綠假單胞菌生物膜引起的廣泛耐藥研究,2021.10-2023.10,5萬元,在研,主持
5、山西省科學技術廳自然科學基金,201901D111390,神經外科術后中樞神經系統感染病原學流行病學及抗菌藥物的PK/PD研究,2019.9-2022.9,5萬元,在研,主持
6、山西地區碳青霉烯類耐藥的肺炎克雷伯菌分子流行病學特點及治療對策研究,山西省科學技術廳社會發展項目,項目編號201803D31124
7、喹諾酮類藥物對銅綠假單胞菌生物膜喹諾酮信號(PQS)系統的機制研究,山西省科學技術廳自然科學基金,項目編號201601D11113
8、血糖水平對銅綠假單胞菌生物膜形成影響的研究,山西省衛生廳科技攻關項目,項目編號2014045
代表性論著
Anti-bacteria, anti-biofilm, and anti-virulence activity of the synthetic compound MTEBT-3 against carbapenem-resistant Klebsiella pneumoniae strains ST3984,2024,IF=3.3(通訊作者)
Dual osmotic controlled release platform for antibiotics to overcome antimicrobial-resistant infections and promote wound healing,2024,IF=10.5(共同通訊作者)
Characteristics, Outcomes, and Clinical Indicators of Bloodstream Infections in Neutropenic Patients with Hematological Malignancies: A 7-Year Retrospective Study,2023,IF=2.9(通訊作者)
Molecular Epidemiology of Carbapenem Resistant Klebsiella pneumoniae in Northern China: Clinical Characteristics, Antimicrobial Resistance, Virulence and Geographic Distribution,2023,IF=2.9(通訊作者)
Prevalence of antimicrobial use and healthcare-associated infections in China: Results from the first point prevalence survey in 18 hospitals in Shanxi Province, 2023,IF=3.7(通訊作者)
Antibiotic resistance and virulence characteristics of four carbapenem-resistant Klebsiella pneumoniae strains coharbouring blaKPC and blaNDM based on whole genome sequences from a tertiary general teaching hospital in central China between 2019 and 2021, 2023, IF=3.3(通訊作者)
Moderating effects of humanistic care and socioeconomic status on the relationship among pain intensity, psychological factors, and psychological function in adults with cancer pain from a province of China: A cross-sectional study, 2023, IF=3.2(通訊作者)
Bacteriological Profile and Antimicrobial Susceptibility Patterns of Gram-Negative Bloodstream Infection and Risk Factors Associated with Mortality and Drug Resistance: A Retrospective Study from Shanxi, China, 2022, IF=2.9(通訊作者)
Mortality Risk Factors and Prognostic Analysis of Patients with Multi-Drug Resistant Enterobacterales Infection, 2022, IF=2.9(通訊作者)
Three Novel Sequence Types Carbapenem-Resistant Klebsiella pneumoniae Strains ST5365, ST5587, ST5647 Isolated from Two Tertiary Teaching General Hospitals in Shanxi Province, in North China: Molecular Characteristics, Resistance and Virulence Factors, 2022, IF=2.9(通訊作者)
Epidemiology of patients with central nervous system infections, mainly neurosurgical patients: a retrospective study from 2012 to 2019 in a teaching hospital in China, 2021(通訊作者)
Co-Production of NDM-1, CTX-M-9 Family and mcr-1 in a Klebsiella pneumoniae ST4564 Strain in China, 2021(通訊作者)
Polymorphism of MTHFR C677T Gene and the Associations with the Severity of Essential Hypertension in Northern Chinese Population, 2020(通訊作者)
Emergence of NDM-5-Producing Carbapenem Resistant Klebsiella pneumoniae and SIM-Producing Hypervirulent Klebsiella pneumoniae Isolated from Aseptic Body Fluid in a Large Tertiary Hospital, 2017–2018: Genetic Traits of blaNDM-Like and blaSIM-Like Genes as Determined by NGS, 2020(通訊作者)
Successful control of the first carbapenemresistant Klebsiella pneumoniae outbreak in a Chinese hospital 2017–2019, 2020(通訊作者)
The role of clinical pharmacist trainees in medication reconciliation process at hospital admission, 2020(通訊作者)
The effect of inpatient pharmaceutical care on nephrotic syndrome patients after discharge: a randomized controlled trial, 2020(通訊作者)